Prognosis of chronic lymphocytic leukemia: a multivariate regression analysis of 325 untreated patients
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Prognosis of chronic lymphocytic leukemia: a multivariate regression analysis of 325 untreated patients.
Three hundred twenty-five previously untreated patients with chronic lymphocytic leukemia were analyzed to identify significant prognostic factors for survival. Univariate analysis identified the following characteristics associated with survival: (1) clinical characteristics: age, race, sex, performance status, lymphadenopathy, and hepatosplenomegaly; (2) hematologic parameters: WBC count, abs...
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I N CHRONIC lymphocytic leukemia (CLL), a centam number of prognostic factors have been isolated. Some of them were grouped by Rai et al.’ in a clinical staging system that has been widely acepted and venified.2 However, some attempts to improve this classification have been carried out.79 Recently, an International Workshop on CLL’#{176}has recommended a modified system for CLL staging, which ...
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A multivariate survival analysis by means of Cox's multiple regression model was performed on a series of 150 consecutive patients with chronic lymphocytic leukemia (CLL) from a single institution. In addition to the well established prognostic factors, such as anemia and thrombocytopenia, a marked prognostic value of the degree of absolute peripheral lymphocytosis emerged from this analysis. T...
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ژورنال
عنوان ژورنال: Blood
سال: 1987
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v69.3.929.bloodjournal693929